Results 51 to 60 of about 6,272,149 (253)
Jurnal Magister Pendidikan MatematikaThis study aims to determine the implementation of the flipped classroom model in mathematics learning on the building materials of flat side spaces, cubes and blocks on students' spatial mathematical ability.
Yoseph Watratan +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Role of Cognitive Abilities in Project-Based Teaching: A Mixed Methods Study
Behavioral SciencesCognitive abilities are foundational to complex tasks, which may be also important in complex project-based teaching. However, the role of teachers’ cognitive abilities in project-based teaching is still unknown.
Li Wang, Chunli Zhang
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Spatial ability for university biology education [PDF]
, 2018 Studying and pursuing careers of Science, Technology, Engineering, and Mathematics (STEM) fields demand spatial ability. Completing a university degree in biology is no exception. The aim of this study is to summarize key findings showing that there is a
Juan C. Castro-Alonso +5 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
From Rare Mutations to Normal Variation: Genetic Association Study of Mathematical, Spatial, and General Cognitive Abilities [PDF]
Psychology in Russia: State of Art, 2018 Background. Behavioral genetic fndings suggest that complex traits, such as mathematical ability, general cognitive ability (intelligence; g), and spatial ability, are infuenced by many common genetic variants of very small efects that operate across ...
Maja Rodic +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A Review of Spatial Ability Research [PDF]
, 2019 Spatial ability research has been approached from several psychological vantages since its beginnings in the late 1800s. This contribution attempts a summation of spatial ability research, beginning with a historical vignette and a major section on each ...
Mohler, James L.
core +1 more source