Results 61 to 70 of about 4,294,785 (258)
, 2009 This article describes attempts that cross-fertilize spatial science and critical geographies and challenge the analytical/quantitative versus critical/qualitative distinction existing across human geography. The article is organized on the basis of criticisms of positivist quantitative geography; it discusses both (early) attempts to articulate the ...
openaire +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sensing motion using spectral and spatial analysis of WLAN RSSI [PDF]
, 2007 In this paper we present how motion sensing can be obtained just by observing the WLAN radio signal strength and its fluctuations. The temporal, spectral and spatial characteristics of WLAN signal are analyzed.
Havinga, P.J.M. +3 more
core +4 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Discursive design thinking: the role of explicit knowledge in creative architectural design reasoning [PDF]
, 2010 The main hypothesis investigated in this paper is based upon the suggestion that the discursive reasoning in architecture supported by an explicit knowledge of spatial configurations can enhance both design productivity and the intelligibility of design ...
Bertel +16 more
core +1 more source
Environmental Research Letters, 2020 The effect of air temperature on photosynthesis is important for the terrestrial carbon cycle. The optimum air temperature for photosynthesis is one of the major parameters in data-driven and process-based photosynthesis models that estimate the gross ...
Qing Chang +7 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Path, theme and narrative in open plan exhibition settings [PDF]
, 2003 Three arguments are made based on the analysis of science exhibitions. First,sufficiently refined techniques of spatial analysis allow us to model the impact oflayout upon visitors' paths, even in moderately sized open plans which allow almostrandom ...
Dalton, Ruth +3 more
core
Car dependence in England and Wales: spatial inequalities and implications for a just transition
Frontiers in Sustainable CitiesThis paper explores the nuances of car dependence in England and Wales by identifying four distinct archetypes that span structural and conscious forms. Employing the 2011 England and Wales Census, archetype prevalence is mapped across the study area at ...
Maria Wood +5 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source