Results 81 to 90 of about 6,818,996 (307)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Finding the Answer in Space: The Mental Whiteboard Hypothesis on Serial Order in Working Memory
Frontiers in Human Neuroscience, 2014 Various prominent models on serial order coding in working memory build on the notion that serial order is achieved by binding the various items to-be-maintained to fixed position markers.
Elger eAbrahamse +3 more
doaj +1 more source
A Dynamic Interplay within the Frontoparietal Network Underlies Rhythmic Spatial Attention.
Neuron, 2018 Classic studies of spatial attention assumed that its neural and behavioral effects were continuous over time. Recent behavioral studies have instead revealed that spatial attention leads to alternating periods of heightened or diminished perceptual ...
I. Fiebelkorn, M. Pinsk, S. Kastner
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Vision, 2018 Attention is engaged differently depending on the type and utility of an attentional cue. Some cues like visual transients or social gaze engage attention effortlessly.
Dana A. Hayward, Jelena Ristic
doaj +1 more source
Visual-Spatial Attention in Developmental Dyslexia
Cortex, 2000 Orienting and focusing of visual attention are two processes strictly involved in reading. They were studied in a group of dyslexic children and normal readers. Shifting of attention by both peripheral and central visual cues was studied by means of the covert orienting paradigm.
A. Facoetti +4 more
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Frontiers in Human Neuroscience, 2012 Behavioral, neuropsychological, and neuroimaging data support the idea that numbers are represented along a mental number line (MNL), an analogical, visuo-spatial representation of number magnitude.
Konstantinos ePriftis +4 more
doaj +1 more source
Topographic specificity of alpha power during auditory spatial attention
bioRxiv, 2019 Visual and somatosensory spatial attention both induce parietal alpha (7-14 Hz) oscillations whose topographical distribution depends on the direction of spatial attentional focus.
Yuqi Deng, I. Choi, B. Shinn-Cunningham
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source