Results 41 to 50 of about 589,072 (264)
Revista Enfermagem UERJ, 2012 Estudo exploratório de campo com o objetivo de identificar os mecanismos de invasão do espaço pessoal e da territorialidade do idoso hospitalizado e os gestos e posturas corporais do profissional de saúde aplicados a favor dessa interação.
Teresa Cristina Prochet +1 more
doaj
ISPRS International Journal of Geo-Information, 2021 The factors affecting tourist behavior are complex and diverse, but research on its effect from a purely spatial perspective is still limited. The aim of this paper is to explore the dichotomous interaction between tourists and islands: the behavioral ...
Xintao Ma, Yuna Hu, Yongwei Liu
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Evoking embodiment in immersive geosimulation environments
Annals of GISWe tackle the issue of how one might close the gap between geographies of people’s behavioural experiences and computer models designed to depict those geographies as simulations.
Paul M. Torrens, Ryan Kim
doaj +1 more source
Spatial Characteristics of Twitter Users—Toward the Understanding of Geosocial Media Production
ISPRS International Journal of Geo-Information, 2017 Social media is a rich source of spatial data but it has also many flaws and well-known limitations, especially in regard to representation and representativeness, since very little is known about the demographics of the user population. At the same time,
Michal Rzeszewski, Lukasz Beluch
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Collective behavior in the spatial spreading of obesity [PDF]
Scientific Reports, 2012 9 pages, 4 ...
Gallos, Lazaros K. +4 more
openaire +5 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Journal of Asian Architecture and Building Engineering, 2022 Suburban village tourism is supposed to promote happiness. However, as tourists swarm in, suburban village community spaces tend to become spaces of conflict between diverse groups.
Jie Zheng +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source