Results 61 to 70 of about 589,072 (264)

Environmental Factors, Spatial Behavior, and Unit-Based Design in Dementia Care: A Case Study of Three Long-Term Care Facilities in Xi’an, China

open access: yesBuildings
Older adults with dementia in long-term care facilities often become lost, enter unintended rooms, and develop greater dependence on care staff as a result of visuospatial impairment.
Dian Zhou, Pengwen Wang
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Agency Through Design: Behavior-Specific Use Patterns of Horses Across Four Different Turnout Areas in the Netherlands

open access: yesInternational Journal of Equine Science
Equine turnout areas are commonly designed to maximize open space. However, research in more naturalistic settings suggests that horses use landscape features selectively.
Inga Wolframm   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Beyond Environmental Comfort: The Influence of Functional Attractors on Student Spatial Behavior in University Campuses

open access: yesArchitecture
University campus design frequently emphasizes environmental comfort metrics, like shade provision and solar exposure, to optimize outdoor space usage. Nonetheless, the degree to which these ambient elements affect real user behavior remains ambiguous in
Raneem Anwar   +3 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Some aspects about the spatial dependence index for variability of soil attributes

open access: yesCiência Rural, 2018
: The main purpose of this article was to evaluate the behavior and relationship of the range and components of SDI (Spatial Dependence Index) in general and in function of field factors such as soil types, type of attribute and soil layers.
Eduardo Lucas Ensslin dos Santos   +5 more
doaj   +1 more source

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