Results 81 to 90 of about 589,072 (264)

An in silico model for determining the influence of neuronal co-activity on rodent spatial behavior. [PDF]

J Neurosci Methods, 2022
Srinivasan A, Srinivasan A, Riceberg JS, Goodman MR, Guise KG, Shapiro ML.   +5 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Sex Differences in the Spatial Behavior Functions of Adult-Born Neurons in Rats. [PDF]

eNeuro, 2022
O'Leary TP, Askari B, Lee BH, Darby K, Knudson C, Ash AM, Seib DR, Espinueva DF, Snyder JS.   +8 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Spatial behavior of hepatitis A, MMR, and varicella vaccination coverage in the state of Minas Gerais, 2020. [PDF]

Rev Bras Epidemiol, 2023
Oliveira GCCF, Arroyo LH, Vimieiro AM, Gusmão JD, Oliveira VC, Guimarães EAA.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Spatial Behavior and Habitat Use of Two Sympatric Bat Species. [PDF]

Animals (Basel), 2021
Starik N, Göttert T, Zeller U.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Transformation of spatial representations along hippocampal circuits

iScience
Summary: The hippocampus is thought to provide the brain with a cognitive map of the external world by processing various types of spatial information.
Bérénice Gandit, Lorenzo Posani, Chun-Lei Zhang, Soham Saha, Cantin Ortiz, Manuela Allegra, Christoph Schmidt-Hieber   +6 more
doaj   +1 more source

Fitness, risk taking, and spatial behavior covary with boldness in experimental vole populations. [PDF]

Ecol Evol, 2022
Eccard JA, Herde A, Schuster AC, Liesenjohann T, Knopp T, Heckel G, Dammhahn M.   +6 more
europepmc   +1 more source