Results 41 to 50 of about 304,521 (259)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Energy-Aware Spatial and Temporal Resolution Selection for Per-Title Encoding

IEEE Access
Video streaming has become an integral part of our digital lives, driving the need for efficient video delivery. With the growing demand for seamless video delivery, adaptive video streaming has emerged as a solution to support users with varying device ...
Mohammad Ghasempour, Hadi Amirpour, Christian Timmerer   +2 more
doaj   +1 more source

An index of floodplain surface complexity [PDF]

Hydrology and Earth System Sciences, 2016
Floodplain surface topography is an important component of floodplain ecosystems. It is the primary physical template upon which ecosystem processes are acted out, and complexity in this template can contribute to the high biodiversity and productivity ...
M. W. Scown, M. C. Thoms, N. R. De Jager
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Calibration for Improving the Medium-Range Soil Forecast over Central Tibet: Effects of Objective Metrics’ Diversity

Atmosphere
The high spatial complexities of soil temperature modeling over semiarid land have challenged the calibration–forecast framework, whose composited objective lacks comprehensive evaluation.
Yakai Guo, Changliang Shao, Guanjun Niu, Dongmei Xu, Yong Gao, Baojun Yuan   +5 more
doaj   +1 more source

Structural Complexity and Informational Transfer in Spatial Log-Gaussian Cox Processes

Entropy, 2021
The doubly stochastic mechanism generating the realizations of spatial log-Gaussian Cox processes is empirically assessed in terms of generalized entropy, divergence and complexity measures.
Adriana Medialdea, José Miguel Angulo, Jorge Mateu   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Complex Quadrature Spatial Modulation

ETRI Journal, 2017
In this paper, we propose a spatial modulation (SM) scheme referred to as complex quadrature spatial modulation (CQSM). In contrast to quadrature spatial modulation (QSM), CQSM transmits two complex signal constellation symbols on the real and quadrature spatial dimensions at each channel use, increasing the spectral efficiency.
Manar Mohaisen, Saetbyeol Lee
openaire   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source