Results 61 to 70 of about 202,726 (265)

Mekân Dizimi: Mekânsal Örgütlenmeyi Grafikleştirme, Sayısallaştırma, Okuma ve Yorumlama

open access: yesPLANARCH - Design and Planning Research
Mekân dizimi, mekânsal örgütlenmeler arasındaki benzerlik ya da farklılıkları analiz etmek için kullanılan bir yöntemdir. Bu çalışma, bu yöntemin kullanımına ilişkin detayları bir uygulama üzerinden ortaya çıkarmayı amaçlamaktadır.
Ayhan Bekleyen
doaj   +1 more source

Seeing the Axial Line: Evidence from Wayfinding Experiments

open access: yesBehavioral Sciences, 2014
Space-geometric measures are proposed to explain the location of fixations during wayfinding. Results from an eye tracking study based on real-world stimuli are analysed; the gaze bias shows that attention is paid to structural elements in the built ...
Beatrix Emo
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

A trajectory planning method for the redundant manipulator based on configuration plane

open access: yesInternational Journal of Advanced Robotic Systems, 2021
This study focuses on the method of trajectory planning of spatial obstacle avoidance for redundant manipulators based on configuration plane method.
Yanhui Wei   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Assessing the spatial equity of the aged care institutions based on the improved potential model: a case study in Shanghai, China

open access: yesFrontiers in Public Health
With the spread of an aging society, the demand for aged care institutions among older adults is increasing. The inadequate supply and distribution of aged care institutions have led to an increasing concern about spatial equity in aged care institutions.
Chenyang Wang, Xiuli Geng, Xiuli Geng
doaj   +1 more source

SPACE SYNTAX ANALYSES IN DEFINING THE CONNECTION OF DEVELOPMENT CENTERS IN BALIKPAPAN

open access: yesDimensi: Journal of Architecture and Built Environment, 2021
Old town means an historic or original core of a city which signifies the city’s origin growth. When the city develops and expands its built area, the emergence of a new development center will be inevitable.
Sherlia   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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