Results 51 to 60 of about 226,967 (265)

The Spatial Logic of Privacy: Uncovering Privacy Patterns in Shared Housing Environments

open access: yesBuildings
In response to the growing relevance of shared housing models such as co-living and co-housing, this study investigates how spatial configuration affects the experience and negotiation of privacy in shared domestic environments.
Ana Moreira, Francisco Serdoura
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Climate-Responsive Design for Sustainable Housing: Thermal Comfort, Spatial Configuration, and Environmental Satisfaction in Subtropical Void Decks

open access: yesBuildings
With rapid urbanization and intensifying climate change impacts, the thermal comfort performance of semi-outdoor spaces has emerged as a critical issue in sustainable urban design and housing development.
Shan Chen, Jinbo Feng, Fei Xue, Qiong Hu
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Empirical Assessment of Audience Attraction in Shopping Centres Based on the Notion of Social Sustainability

open access: yesTehnički Glasnik
This study addresses the contemporary focus of commercial spaces on enhancing social, cultural, and economic experiences to attract individuals, prompting architects to align designs with audience objectives. It explores social sustainability dimensions,
Reza Askarizad   +2 more
doaj   +1 more source

Les AOC en France des débuts à nos jours : la complexité d’une construction dans l’espace et dans le temps

open access: yesM@ppemonde, 2019
The Appellations Françaises d'Origine Contrôlée, which have become Appellations d'Origine Protégée, divide France according to its large river valleys, areas that have historically been favorable to exporting wine.
François Legouy, Sébastien Dallot
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

THE TOPOLOGY OF SUBSPACES OF THE CONFIGURATION SPACE OF SPATIAL PENTAGONS

open access: yesJP Journal of Geometry and Topology, 2023
We assume that four bond angles of a spatial hexagon are . According to the choice of the four bond angles, we define the configuration spaces , and . We determine the topological types of these spaces.
openaire   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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