Results 71 to 80 of about 2,181,625 (282)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Duality Between Spatial and Angular Shift in Optical Reflection [PDF]

open access: yes, 2009
We report a unified representation of the spatial and angular Goos-Hanchen and Imbert-Fedorov shifts that occur when a light beam reflects from a plane interface. We thus reveal the dual nature of spatial and angular shifts in optical beam reflection. In
A. Aiello   +6 more
core   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Spatial context-aware person-following for a domestic robot [PDF]

open access: yes, 2008
Domestic robots are in the focus of research in terms of service providers in households and even as robotic companion that share the living space with humans. A major capability of mobile domestic robots that is joint exploration of space.
Hanheide, Marc   +2 more
core  

Weakly-Supervised Spatial Context Networks

open access: yes2019 IEEE Winter Conference on Applications of Computer Vision (WACV), 2019
We explore the power of spatial context as a self-supervisory signal for learning visual representations. In particular, we propose spatial context networks that learn to predict a representation of one image patch from another image patch, within the same image, conditioned on their real-valued relative spatial offset.
Wu, Zuxuan   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Incorporating Superpixel Context for Extracting Building From High-Resolution Remote Sensing Imagery

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Extracting building from high-resolution (HR) remote sensing imagery (RSI) serves a variety of areas, such as smart city, environment management, and emergency disaster services.
Fang Fang   +6 more
doaj   +1 more source

Spatial Autocorrelation in a Retail Context [PDF]

open access: yes
This paper describes and applies the weighted least squares (WLS) technique that corrects for spatial autocorrelation in the residuals of hedonic regressions. Most empirical studies to date have focused on spatial autocorrelation in the housing market, i.
Charles C. Cartern, William J. Haloupek
core  

The topological strong spatial mixing property and new conditions for pressure approximation [PDF]

open access: yes, 2014
In the context of stationary $\mathbb{Z}^d$ nearest-neighbour Gibbs measures $\mu$ satisfying strong spatial mixing, we present a new combinatorial condition (the topological strong spatial mixing property (TSSM)) on the support of $\mu$ sufficient for ...
Briceño, Raimundo
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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