Results 31 to 40 of about 117,286 (265)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
GPT-Based Text-to-SQL for Spatial Databases
ISPRS International Journal of Geo-InformationText-to-SQL for spatial databases enables the translation of natural language questions into corresponding SQL queries, allowing non-experts to easily access spatial data, which has gained increasing attention from researchers.
Hui Wang +4 more
doaj +1 more source
Energies, 2019 The paper presents a holistic and quantitative model of social gamification in a smart city, which is likely to stimulate the photovoltaic panels installation. The coupling of multi-agent systems, GIS tools, demographic data, and a spatial knowledge base
Robert Olszewski +3 more
doaj +1 more source
Resource Capacitated Collective Travel Planning in Spatial Databases
IEEE Access, 2020 The widespread use of GPS smart devices has allowed users to collect location information in real-time, leading to the emergence of ride-sharing services based on users' locations. Ride-sharing services have become effective services that reduce the cost
Junkyu Lee, Seog Park
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Journal of Spatial Information Science, 2020 The systems community in both academia and industry has tremendous success in building widely used general purpose systems for various types of data and applications.
Mohamed F. Mokbel
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source