Results 51 to 60 of about 437,980 (285)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Fast Component Density Clustering in Spatial Databases: A Novel Algorithm
Information, 2022 Clustering analysis is a significant technique in various fields, including unsupervised machine learning, data mining, pattern recognition, and image analysis.
Bilal Bataineh
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Automatic Calculation of 3D Characteristics of a Cadastral Parcel for the Purposes of Mass Valuation
Kartografija i Geoinformacije, 2006 Valuation of real estate is an important factor in the economic and political development of a modern state. Modern real estate valuation systems at national level are based on spatial data, both cadastral and topographic, which are maintained using ...
Hrvoje Matijević +2 more
doaj
Spatial ability, urban wayfinding and location-based services:a review and first results [PDF]
, 2004 Location-Based Services (LBS) are a new industry at the core of which are GISand spatial databases. With increasing mobility of individuals, the anticipatedavailability of broadband communications for mobile devices and growingvolumes of location ...
Li, C
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Efficient k-NN Trajectory Queries on Mobility Databases
ISPRS International Journal of Geo-InformationThe rapid adoption of GPS-enabled mobile devices has produced massive trajectory datasets that drive modern applications in traffic prediction, logistics, and spatio-temporal analytics.
Linghui Lou +2 more
doaj +1 more source
Knowledge discovery in spatial databases through qualitative spatial reasoning [PDF]
, 2000 Human beings use qualitative identifiers extensively to simplify reality and to perform spatial reasoning more efficiently. Organisational databases usually store geographic identifiers, like addresses or postcodes, which spatial component is not ...
Amaral, Luís, Santos, Maribel Yasmina
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