Results 41 to 50 of about 117,366 (264)

Resource Capacitated Collective Travel Planning in Spatial Databases

open access: yesIEEE Access, 2020
The widespread use of GPS smart devices has allowed users to collect location information in real-time, leading to the emergence of ride-sharing services based on users' locations. Ride-sharing services have become effective services that reduce the cost
Junkyu Lee, Seog Park
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Thinking spatial

open access: yesJournal of Spatial Information Science, 2020
The systems community in both academia and industry has tremendous success in building widely used general purpose systems for various types of data and applications.
Mohamed F. Mokbel
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Automatic Calculation of 3D Characteristics of a Cadastral Parcel for the Purposes of Mass Valuation

open access: yesKartografija i Geoinformacije, 2006
Valuation of real estate is an important factor in the economic and political development of a modern state. Modern real estate valuation systems at national level are based on spatial data, both cadastral and topographic, which are maintained using ...
Hrvoje Matijević   +2 more
doaj  

Fast Component Density Clustering in Spatial Databases: A Novel Algorithm

open access: yesInformation, 2022
Clustering analysis is a significant technique in various fields, including unsupervised machine learning, data mining, pattern recognition, and image analysis.
Bilal Bataineh
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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