Results 81 to 90 of about 5,565,979 (320)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

UV-Diagram: A Voronoi Diagram for Uncertain Spatial Databases [PDF]

open access: yes, 2013
published_or_final_versio
Chen, J   +4 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Exploiting Information-Centric Networking to Federate Spatial Databases

open access: yesIEEE Access, 2019
This paper explores the methodologies, challenges, and expected advantages related to the use of the information-centric network (ICN) technology for federating spatial databases.
Andrea Detti   +2 more
doaj   +1 more source

Topological queries in spatial databases

open access: yesProceedings of the fifteenth ACM SIGACT-SIGMOD-SIGART symposium on Principles of database systems, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Papadimitriou, CH., Suciu, D., Vianu, V.
openaire   +2 more sources

Issues in spatial microsimulation estimation: a case study of child poverty [PDF]

open access: yes
Spatial microsimulation techniques have become an increasingly popular way to fulfil the need for generating small area data estimates. Nevertheless, this technique poses numerous methodological challenges, including those that relate to fundamental ...
Ann Harding   +4 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Logical aspects of spatial databases [PDF]

open access: yes, 2011
Spatial data and first-order logic - Capturing first-order geometric properties - First-order topological properties of plain sets - Conclusion on first-order topological properties - Point-based logics for geometric queries - Plane graphs - Spatial datalog and first-order logic extend with a while-loop - First-order logic extended with transitive ...
KUIJPERS, Bart, VAN DEN BUSSCHE, Jan
openaire   +2 more sources

Subgrade geology beneath railways in Manchester [PDF]

open access: yes, 2005
It is not sufficient to identify fine-grained soils, only, as locations for potential subgrade problems as could be done using a traditional 2D geological map.
Freeborough, K.   +5 more
core  

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