Results 91 to 100 of about 933,538 (267)
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Identifying levers of urban neighbourhood transformation using serious games
npj Urban SustainabilityGrowing urban population and contemporary urban systems lock-in unsustainable urban development pathways, deteriorating the living quality of urban dwellers.
Johann S. Schuur +3 more
doaj +1 more source
InformationThe valuation of real estate is a fundamental process for the proper functioning of the market and the formulation of public policies. The mother of the traditional methodologies is the comparative method, which is based on data that is often incomplete ...
Nikolaos Karanikolas +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingMonitoring the behavior of surge-type glaciers is important for our understanding of glacier dynamics. However, in central East Greenland, one of the two clusters of surge-type glaciers in Greenland, only a few studies recorded the detailed surge ...
Xiaohan Yuan, Zixiang Sun, Gang Qiao
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The European Spatial Development Perspective
European Journal of Spatial Development, 2001 Item does not contain ...
openaire +3 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
European Journal of Spatial DevelopmentCross-border regions exhibit distinct characteristics in the development of cooperative relations, influenced by international and national conditions at central, regional, and local levels.
Małgorzata Leśniak-Johann +2 more
doaj +1 more source