Results 101 to 110 of about 3,205,346 (307)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The greener, the better? A comprehensive framework for studying the effect of urban green spaces on subjective well-being

open access: yesDiscover Cities
Urban green spaces (UGS) are increasingly appraised as critical elements of contemporary urban landscapes, offering multiple benefits that directly and indirectly influence residents’ subjective well-being (SWB).
Elli Papastergiou   +3 more
doaj   +1 more source

Changing of the spatial development means and institution in hungary after the change of regime [PDF]

open access: yes
Before 1990, regional development policy as a governmental function was of secondary importance. Although economic planning, control and management were based on sectoral principles, regional processes contributed towards an equilibrium in the sense that
Krisztina Sóvágó, Valéria Jusztin
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Planning Blue–Green Infrastructure for Facing Climate Change: The Case Study of Bucharest and Its Metropolitan Area

open access: yesUrban Science
Planning for a green–blue infrastructure system around big cities, having the shape of a belt, to connect natural areas—such as green spaces, water, and agricultural land—is a solution for mitigating the challenges of climate change and urban sprawl.
Antonio-Valentin Tache   +2 more
doaj   +1 more source

Incorporating Spatial Complexity into Economic Models of Land Markets and Land Use Change [PDF]

open access: yes
Recent work in regional science, geography, and urban economics has advanced spatial modeling of land markets and land use by incorporating greater spatial complexity, including multiple sources of spatial heterogeneity, multiple spatial scales, and ...
Chen, Yong   +2 more
core   +1 more source

Landmines and Spatial Development

open access: yes, 2018
Landmine contamination affects the lives of millions in many conflict-ridden countries long after the cessation of hostilities. Yet, little research exists on its impact on post-conflict recovery. In this study, we explore the economic consequences of landmine clearance in Mozambique, the only country that has moved from "heavily-contaminated" in 1992 ...
Giorgio Chiovelli   +2 more
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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