Results 101 to 110 of about 3,128,751 (237)

TECHNIQUES AND METHODS OF GIS FOR REGIONAL DEVELOPMENT [PDF]

open access: yes
The paper presents some techniques and methods of geographic informatics systems, adapted and applied to the regional development applications. The characteristics of spatial databases, as they are required for regional applications are presented in the ...
Adriana REVEIU
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

The aspect of space in the concept of sustainable development: Overview and consequences for research [PDF]

open access: yes
The discussion on sustainable development reflects in various regard an important spatial aspect. In its context, spatial and regional sciences integrate important impulses and provide important contributions to the further development and ...
Gerd Lintz
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Shape up: An eye-tracking study of preschoolers' shape name processing and spatial development. [PDF]

open access: yesDev Psychol, 2017
Verdine BN   +4 more
europepmc   +1 more source

Spatial aspects of the design and targeting of agricultural development strategies: [PDF]

open access: yes
Two increasingly shared perspectives within the international development community are that (a) geography matters, and (b) many government interventions would be more successful if they were better targeted.
Dai, Aiguo   +4 more
core  

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

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