Results 131 to 140 of about 292,395 (311)

Elevation-based Differentiation in Moisture and Nutrients of Sedimentary Layer in the Water-Level Fluctuation Zone of the Three Gorges Reservoir, China

Shuitu Baochi Xuebao
［Objective］ To investigate the elevation-based differentiation in moisture and nutrients of sedimentary layer in the water-level fluctuation zone (WLFZ) and provide a scientific basis for reservoir management.
HE Pingsheng, LI Jinlin, HE Xiubin, TANG Qiang, WU Shengjun, HUANG Ping   +5 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Spatial interaction modeling of interregional commodity flows [PDF]

Understanding the determinants of interregional commodity flows is critical for both transportation infrastructure planning (highways, railroad tracks, river/port facilities) and regional development policies (location of activities, reducing regional ...
Guldmann, Jean-Michel, Celik, H. Murat
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

An analysis of a spatial and economic structure in a region comprising the different kinds of competition [PDF]

A country or a vast region usually comprises different kinds of spatial competition, a free-entry competition, imperfective competition, and a local monopoly, in its economic system: While many firms concentrate on a place and formulate the competitive ...
Ishikawa, Toshiharu
core  

Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt

, 2004
The forkhead transcription factor FOXN1 is required for normal cutaneous and thymic epithelial development. Mutations in FOXN1 give rise to the nude phenotype in mice, rats and man. However, the genes that are regulated by FOXN1 are unknown.
Ofstad, T.A., David M. Prowse, Douglas H. Campbell, Janes, Sam M., Janes, S.M., Prowse, D.M., Prowse, David M., Ofstad, Tyler A., Sam M. Janes, Fiona M. Watt, Watt, F.M., Tyler A. Ofstad, Watt, Fiona M., Campbell, Douglas H., Campbell, D.H.   +14 more
core   +1 more source

Evolution and Driving Factors of Ecosystem Service Value in the Henan Section of the Yellow River Basin at Different Grid Scales

Ecologies
Advancing ecological civilization in the Yellow River Basin requires a nuanced understanding of the spatiotemporal evolution of ecosystem service value (ESV) and its underlying drivers, which are fundamental to regional sustainable development.
Zihan Wang, Yishuo Gu, Meng Zhang, Tianxiao Li   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source