Results 51 to 60 of about 292,395 (311)

Space-time evolution of the average river flow in Transylvania Depression [PDF]

open access: yesAerul şi Apa: Componente ale Mediului, 2018
Transylvania's physico-geographic factors distinguish it as a well-structured depression unit. Climate and relief features give it an unitary systemic functioning, which can be said about river water runoff.
G. PANDI, M. VIGH
doaj   +1 more source

Method for extracting stressed rock crack based on light reflectivity mutation

open access: yesGong-kuang zidonghua, 2022
The crack identification and extraction is the basis of understanding the evolution law of surrounding rock cracks. The existing methods for extracting stressed rock cracks based on visible light photos are poor in extracting the cracks of complex rocks (
GAO Xiang, GAO Yanan
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Multiproduct firms and product differentiation : a survey [PDF]

open access: yes, 2001
We start the survey by reviewing the implications of horizontal and vertical product differentiation on market structure under the assumption of single-product firms.
Manez, Juan A., Waterson, Michael
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Spatial Differentiation Characteristics, Driving Mechanisms, and Governance Strategies of Rural Poverty in Eastern Tibet

open access: yesLand
Rural areas in Tibet, with its complex terrain, fragile ecology, and poor facilities, are subject to a combination of social–ecological system elements, facing the typical risks of recurrent, marginal, and potential poverty.
Jian Tian   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A runoff system restores the principle of minimum differentiation [PDF]

open access: yes, 1999
We show that the principle of minimum differentiation holds in two-round elections, for any number of candidates, regardless of the presence of entrants, or the distribution of voters’ preferences.
Volkerink, B.S.I.   +7 more
core   +1 more source

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