Results 91 to 100 of about 3,279,912 (297)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Mapeando a fecundidade nordestina: 2000-2010

Confins, 2017
The results of the 2010 Demographic Census show that, among the three most populous Brazilian regions (representing more than 80% of the Brazilian population), the Northeast was the region registering the highest rate of population growth between 2000 ...
Morvan de Mello Moreira, Wilson Fusco
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Spatial distribution of Cherenkov radiation in periodic dielectric media

, 2009
The nontrivial dispersion relation of a periodic medium affects both the spectral and the spatial distribution of Cherenkov radiation. We present a theory of the spatial distribution of Cherenkov radiation in the far-field zone inside arbitrary three ...
Bykov V P, Cherenkov P A, Christian Kremers, Dmitry N Chigrin, Jeffrey A, Jelley J V, Joannopoulos J D, Sakoda K, Taflove A   +8 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

POPULATION STRUCTURE OF Heteropsis spp. Kunth (TITICA VINE) IN THE TAPAJÓS NATIONAL FOREST, PARÁ-BRAZIL [PDF]

Revista Árvore
The objective of the present study was to analyze the ecological aspects of Heteropsis spp. Kunth (titica vine) in an area maintained under forest management conditions.
Lizandra Elizeário dos Santos, João Ricardo Vasconcellos Gama, Andrea Araújo da Silva, Marcela Gomes da Silva   +3 more
doaj   +2 more sources

Spatial distribution of the known asteroids [PDF]

Spatial distribution of known asteroids in solar ...
Narin, F.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The spatial distribution of star and cluster formation in M51

, 2008
Aims. We study the connection between spatially resolved star formation and young star clusters across the disc of M51. Methods. We combine star cluster data based on B, V, and I-band Hubble Space Telescope ACS imaging, together with new WFPC2 U-band ...
Alvensleben, Alvensleben, Alvensleven, Alvensleven, Bash, Bastian, Bastian, Bastian, Bastian, Bate, Beech, Bertelli, Bertin, Bik, Boeshaar, Cardelli, Charbonnel, Condon, Contopoulos, Contopoulos, de Grijs, de Grijs, Diaz, Dolphin, Efremov, Efremov, Elmegreen, Elmegreen, Elmegreen, Elmegreen, Elmegreen, Elson, Fall, Feldmeier, García-Burillo, Gieles, Gieles, Girardi, Gomez, Goodwin, H. J. G. L. M. Lamers, Helou, Hill, Holtzman, Hunter, Hwang, Jarrett, Kennicutt, Kennicutt, Kennicutt, Kennicutt, Kennicutt, Kroupa, Lada, Larsen, Larsen, Larsen, Larsen, Larson, Marsh, Meurer, Mihos, Murgia, Murphy, Murphy, Niklas, Niklas, P. Anders, Patrikeev, R. A. Scheepmaker, Roberts, S. S. Larsen, Schaerer, Scheepmaker, Schlegel, Schuster, Tamburro, Tully, Whitmore, Whitmore, Yun, Zhang, Zimmer   +82 more
core   +2 more sources