Results 81 to 90 of about 569,815 (265)
The effect of tinted spectacle lenses on contrast sensitivity and colour vision
African Vision and Eye Health, 2013 Aim: Spectacle wearers often prefer tintedlenses to clear or non-tinted lenses for their protection against harmful radiation, improved cos- mesis, enhancement of visual performance and effects on colour vision.
M. Shaik +6 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Optimization of a digital filter for image focusing evaluation in digital optical microscopy
Технологія та конструювання в електронній апаратурі, 2005 A method is proposed for optimizing a high spatial frequency digital filter used to evaluate image focusing in digital optical microscopy. This method takes into account the dimensional characteristics of the observed object, as well as the parameters ...
V. N. Borovitsky
doaj
Frontiers in Human Neuroscience, 2013 Hemispheric specialization for spatial frequency processing was investigated by measuring the contrast sensitivity curves of sine-wave gratings in 30 left or right brain-damaged patients using different spatial frequencies compared with healthy ...
Natanael Antonio Dos Santos +2 more
doaj +1 more source
Human optokinetic nystagmus and spatial frequency
Journal of Vision, 2015 Optokinetic nystagmus (OKN) is a fundamental oculomotor response to retinal slip generated during natural movement through the environment. The timing and amplitude of the compensatory slow phases (SPs) alternating with saccadic quick phases (QPs) are remarkably variable, producing a characteristic irregular sawtooth waveform.
Jonathan, Waddington +1 more
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source