Results 121 to 130 of about 3,984,310 (349)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
BMC Medical Research Methodology, 2019 Background In the context of environmentally influenced communicable diseases, proximity to environmental sources results in spatial heterogeneity of risk, which is sometimes difficult to measure in the field.
Abdoulaye Guindo +10 more
doaj +1 more source
Journal of the National Cancer Institute, 2018 Background Despite increasing evidence supporting the clinical utility of immune infiltration in the estrogen receptor-negative (ER-) subtype, the prognostic value of immune infiltration for ER+ disease is not well defined.
A. Heindl +5 more
semanticscholar +1 more source
Incorporating Spatial Complexity into Economic Models of Land Markets and Land Use Change [PDF]
Recent work in regional science, geography, and urban economics has advanced spatial modeling of land markets and land use by incorporating greater spatial complexity, including multiple sources of spatial heterogeneity, multiple spatial scales, and ...
Chen, Yong +2 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Spatial Heterogeneity of Glassy Polymer Films
Macromolecules, 2015 By studying the morphology of polystyrene films subjected to a fast structuration method, we demonstrate the spatial heterogeneity of their surface viscoelasticity at temperatures well below the glass transition temperature, Tg. Our results point to a nonrandom arrangement of zones of different elastic modulus deep in the glassy state.
Siretanu, Igor +3 more
openaire +3 more sources
Nature Communications, 2018 The mechanical properties of crystalline materials can be quantitatively described by crystal defects of solute atoms, dislocations, twins, and grain boundaries with the models of solid solution strengthening, Taylor strain hardening and Hall–Petch grain
F. Zhu +4 more
semanticscholar +1 more source
The European Regional Convergence Process, 1980-1995: Do Spatial Regimes and Spatial Dependence Matter? [PDF]
We show in this paper that spatial dependence and spatial heterogeneity matter in the estimation of the b-convergence process among 138 European regions over the 1980-1995 period.
Catherine Baumont +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source