Results 101 to 110 of about 4,411,385 (345)

Overlapping jurisdictions and demand for local public services: does spatial heterogeneity matter? [PDF]

open access: yes
This paper aims to test the existence of vertical interactions in terms of public spending between overlapping local jurisdictions in France using a data set of 110 French municipalities and their corresponding departments in 2001 and 2005.
Alain Guengant   +2 more
core  

Jamming Mechanisms and Density Dependence in a Kinetically-Constrained Model

open access: yes, 2010
We add relaxation mechanisms that mimic the effect of temperature and non-equilibrium driving to the recently-proposed spiral model which jams at a critical density rho_c < 1. This enables us to explore unjamming by temperature or driving at rho_c < rho <
Liu, Andrea J., Shokef, Yair
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Spatial heterogeneity and driving forces of environmental productivity growth in China: Would it help to switch pollutant discharge fees to environmental taxes?

open access: yesJournal of Cleaner Production, 2019
Emission charge policy has recently switched from pollutant discharge fees to environmental taxes in China. Considering spatial heterogeneity, the effects of changes in emission charge policy may subject to different Chinese regions.
Jiayu Wang   +3 more
semanticscholar   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Evaluating the Temporal and the Spatial Heterogeneity of the European Convergence Process, 1980-1999 [PDF]

open access: yes
In this paper, we suggest a general framework that allows testing simultaneously for temporal heterogeneity, spatial heterogeneity and spatial autocorrelation in b-convergence models.
Julie LE GALLO (IERSO, IFReDE-GRES)   +1 more
core   +3 more sources

Hopf Bifurcation in an Oscillatory-Excitatory Reaction-Diffusion Model with Spatial heterogeneity

open access: yes, 2016
We focus on the qualitative analysis of a reaction-diffusion with spatial heterogeneity. The system is a generalization of the well known FitzHugh-Nagumo system in which the excitability parameter is space dependent.
Ambrosio, B.
core   +3 more sources

Selected topics on reaction-diffusion-advection models from spatial ecology

open access: yes, 2020
We discuss the effects of movement and spatial heterogeneity on population dynamics via reaction-diffusion-advection models, focusing on the persistence, competition, and evolution of organisms in spatially heterogeneous environments.
Lam, King-Yeung, Liu, Shuang, Lou, Yuan
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A multiple spatial scales water use simulation for capturing its spatial heterogeneity through cellular automata model [PDF]

open access: yesHydrology and Earth System Sciences
Reliable water use simulation is essential for sustainable water resource planning, especially under intensifying pressures from climate change, population growth, and socio-economic transitions.
J. Zhang   +8 more
doaj   +1 more source

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