Results 81 to 90 of about 3,162,655 (261)

Spatial clustering of measles vaccination coverage among children in sub-Saharan Africa

BMC Public Health, 2017
Background During the past two decades, vaccination programs have greatly reduced global morbidity and mortality due to measles, but recently this progress has stalled.
Tenley K. Brownwright, Zan M. Dodson, Willem G. van Panhuis   +2 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Dual-heterogeneity temporal-spatial network for traffic flow prediction

Journal of King Saud University: Computer and Information Sciences
Urban traffic flow is a typical non-stationary system with pronounced dual-heterogeneity. Here, dual-heterogeneity refers to both temporal and spatial heterogeneity within traffic systems.
Linlong Chen
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The European Regional Convergence Process, 1980-1995: Do Spatial Regimes and Spatial Dependence Matter? [PDF]

We show in this paper that spatial dependence and spatial heterogeneity matter in the estimation of the b-convergence process among 138 European regions over the 1980-1995 period.
Julie Le Gallo, Catherine Baumont, Cem Ertur   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ground‐dwelling mammal diversity responds positively to productivity and habitat heterogeneity in a fire‐prone region

Ecosphere, 2020
Environmental heterogeneity has a consistent, positive effect on species diversity globally, principally due to increased niche space in heterogeneous environments.
Matthew Swan, Fiona Christie, Erin Steel, Holly Sitters, Alan York, Julian Di Stefano   +5 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A multiple spatial scales water use simulation for capturing its spatial heterogeneity through cellular automata model [PDF]

Hydrology and Earth System Sciences
Reliable water use simulation is essential for sustainable water resource planning, especially under intensifying pressures from climate change, population growth, and socio-economic transitions.
J. Zhang, D. Liu, D. Liu, D. Liu, J. Wang, F. Yue, H. Liang, Z. Peng, W. Guan   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source