Results 81 to 90 of about 4,411,385 (345)

Geographical random forests: a spatial extension of the random forest algorithm to address spatial heterogeneity in remote sensing and population modelling

Geocarto International, 2019
Machine learning algorithms such as Random Forest (RF) are being increasingly applied on traditionally geographical topics such as population estimation.
S. Georganos, T. Grippa, Assane Niang Gadiaga, Catherine Linard, M. Lennert, S. Vanhuysse, Nicholus Mboga, E. Wolff, S. Kalogirou   +8 more
semanticscholar   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Soil Spatial Heterogeneity and Systems of Agriculture

Agricultural Science and Practice, 2015
Aim. To consider soil continuality and discreteness as features of heterogeneity manifestation in a soil cover, important for construction of agriculture systems. Methods. Geostatistical research of soil spatial heterogeneity, revealing the contours of a
V. Medvedev
doaj   +1 more source

Spatial heterogeneity in projected leprosy trends in India [PDF]

, 2015
Background: Leprosy is caused by infection with Mycobacterium leprae and is characterized by peripheral nerve damage and skin lesions. The disease is classified into paucibacillary (PB) and multibacillary (MB) leprosy.
Beauclair, Roxanne, Brook, Cara E, Galvani, Alison P, Lietman, Thomas M, Ndeffo-Mbah, Martial, Ngwenya, Olina, Porco, Travis C, Satpathy, Sudhir K, Worden, Lee   +8 more
core   +3 more sources

Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry

Nature Communications, 2019
Tumor-associated macrophages (TAMs), one of the most abundant immune components in gastric cancer (GC), are difficult to characterize due to their heterogeneity.
Yu-Kuan Huang, Minyu Wang, Yu Sun, Natasha Di Costanzo, C. Mitchell, A. Achuthan, J. Hamilton, R. Busuttil, A. Boussioutas   +8 more
semanticscholar   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Testing spatial heterogeneity with stock assessment models.

PLoS ONE, 2018
This paper describes a methodology that combines meta-population theory and stock assessment models to gain insights about spatial heterogeneity of the meta-population in an operational time frame.
Ernesto Jardim, Margit Eero, Alexandra Silva, Clara Ulrich, Lionel Pawlowski, Steven J Holmes, Leire Ibaibarriaga, José A A De Oliveira, Isabel Riveiro, Nekane Alzorriz, Leire Citores, Finlay Scott, Andres Uriarte, Pablo Carrera, Erwan Duhamel, Iago Mosqueira   +15 more
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Quantifying the spatial heterogeneity of geographical flows

Geo-spatial Information Science
Geographical flows describe the movements and connections of materials, energy, and information among locations and are commonly represented by origin-destination (OD) flows (flows for short).
Hua Shu, Tao Pei, Ci Song, Sihui Guo, Jie Chen, Yaxi Liu, Xi Wang, Xiao Chen, Chenghu Zhou   +8 more
doaj   +1 more source