Results 61 to 70 of about 319,235 (305)

Evaluating the Temporal and the Spatial Heterogeneity of the European Convergence Process, 1980-1999 [PDF]

open access: yes
In this paper, we suggest a general framework that allows testing simultaneously for temporal heterogeneity, spatial heterogeneity and spatial autocorrelation in b-convergence models.
Julie LE GALLO (IERSO, IFReDE-GRES)   +1 more
core   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The effects of variable spatial aggregation on lymphatic filariasis transmission

open access: yesParasites & Vectors
Background Elimination of lymphatic filariasis (LF) is a World Health Organization goal, with several countries at or near prevalence thresholds.
Callum Shaw, Angus McLure, Kathryn Glass
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

3D-SHI index for quantifying 3D spatial heterogeneity in big Earth data

open access: yesInternational Journal of Digital Earth
Investigating spatial heterogeneity is a crucial aspect of spatial analysis. Existing studies have primarily focused on measuring 2D geographic distribution, which cannot be directly applied to extensive 3D big earth datasets.
Peijie Sun   +3 more
doaj   +1 more source

Soil Spatial Heterogeneity and Systems of Agriculture

open access: yesAgricultural Science and Practice, 2015
Aim. To consider soil continuality and discreteness as features of heterogeneity manifestation in a soil cover, important for construction of agriculture systems. Methods. Geostatistical research of soil spatial heterogeneity, revealing the contours of a
V. Medvedev
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Testing spatial heterogeneity with stock assessment models.

open access: yesPLoS ONE, 2018
This paper describes a methodology that combines meta-population theory and stock assessment models to gain insights about spatial heterogeneity of the meta-population in an operational time frame.
Ernesto Jardim   +15 more
doaj   +1 more source

Spatial and Temporal Heterogeneity in Founding Patterns

open access: yesOrganization Science, 2003
A growing body of literature suggests that populations of organizations are not homogeneous, but instead comprise distinct subentities. Firms are highly dependent on their immediate institutional and competitive environments. The present paper further explores this issue by focusing on the spatial and temporal sources of industry heterogeneity.
Cattani, Gino   +2 more
openaire   +4 more sources

Housing Risk and Returns in Submarkets with Spatial Dependence and Heterogeneity

open access: yes, 2022
Employing a recently developed panel econometric technique, first, we show that accounting for spatial dependence and heterogeneity yields more accurate risk factor coefficients and abnormal housing returns.
Earl, G   +4 more
core   +1 more source

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