Results 81 to 90 of about 422,181 (302)

Arc index of spatial graphs

open access: yesJournal of Graph Theory, 2018
AbstractBae and Park found an upper bound on the arc index of prime links in terms of the minimal crossing number. In this paper, we extend the definition of the arc presentation to spatial graphs and find an upper bound on the arc index of any spatial graph as where is the minimal crossing number of , is the number of edges, and is the number of
Min Jung Lee, Sungjong No, Seungsang Oh
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A spatial vulnerability index for environmental health

open access: yesEcological Indicators
Extreme natural hazards are increasing in frequency and intensity. These natural changes in our environment, combined with man-made pollution, have substantial economic, social and health impacts globally.
Aiden Price   +3 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Temporal and Spatial Analysis of Negative Emotions in China during the COVID-19 Pandemic

open access: yesBehavioral Sciences
This research aims to explore the spatiotemporal distribution patterns of negative emotions in mainland China during different stages of the COVID-19 pandemic and the external factors influencing this clustering.
Yating Ding, Lin Wu, Zijian Peng, Bo Liu
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Providing a Spatial Index to Evaluate Deteriorated Urban Textures by Geographical Information System and Multi-criteria Decision Making

open access: yes, 2019
The phenomenon of urbanism has caused cities to adopt a new spatial arrangement, and old and deteriorated urban textures receive fewer attention than before. This lack of attention brings several socio-economic and environmental issues for these textures,
Hamid Motieyan
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Investigation on perceptual influence of spatial index on enveloping sound

open access: yes, 2013
December 2013School of ArchitectureThis thesis is to discover the influence of Spatial Index on the region of listener envelopment. Audio engineers often realize the perceptual difference between convolution and conventional artificial reverberation ...
Oh, Jiseong
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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