Results 61 to 70 of about 13,582,146 (349)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

QUANTIFYING EFFECTS OF CHANGING SPATIAL SCALE ON SPATIAL ENTROPY INDEX: USE OF FRACTAL DIMENSION [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Quantifying landscape heterogeneity and its organization at different scales is essential for understanding ecosystems and landscapes. Among hundreds of landscape metrics, entropy-related index represents an efficient tool to quantify and characterize ...
C. J. Wang   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Study of the Agglomeration Characteristics of Cultivated Land in Underdeveloped Mountainous Areas Based on Spatial Auto-Correlation: A Case of Pengshui County, Chongqing, China

open access: yesLand, 2022
The economic and social orientation of cultivated land in underdeveloped mountainous areas is obvious. A study of the spatial agglomeration characteristics of cultivated land quality can provide guidance for regional economic and social development ...
Guanglian Luo   +4 more
doaj   +1 more source

Fair Spatial Indexing: A paradigm for Group Spatial Fairness

open access: yesAdvances in database technology : proceedings. International Conference on Extending Database Technology, 2023
Machine learning (ML) is playing an increasing role in decision-making tasks that directly affect individuals, e.g., loan approvals, or job applicant screening. Significant concerns arise that, without special provisions, individuals from under-privileged backgrounds may not get equitable access to services and opportunities.
Sina Shaham   +2 more
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Measuring the spatial balance of a sample: A new measure based on the Moran's I index [PDF]

open access: yes, 2018
Measuring the degree of spatial spreading of a sample can be of great interest when sampling from a spatial population. The commonly used spatial balance index by Grafström et al.
Tillé, Yves   +3 more
core   +1 more source

The Marine Spatial Planning Index: a tool to guide and assess marine spatial planning

open access: yesnpj Ocean Sustainability, 2023
Marine spatial planning (MSP) has the potential to balance demands for ocean space with environmental protection and is increasingly considered crucial for achieving global ocean goals. In theory, MSP should adhere to six principles, being: (1) ecosystem-
Julie M. Reimer   +5 more
doaj   +1 more source

Quantitative analysis of the spatial diversity of Moraceae in China

open access: yesFrontiers in Ecology and Evolution, 2023
Changes in distribution patterns of economically essential forest species under global change are urgently needed in the scientific forecast, and large-scale spatial modeling is a crucial tool.
Dangui Lu   +5 more
doaj   +1 more source

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