Results 51 to 60 of about 2,234,141 (283)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The arable farmer as the assessor of within-field soil variation [PDF]
, 2010 Feasible, fast and reliable methods of mapping within-field variation are required for precision agriculture. Within precision agriculture research much emphasis has been put on technology, whereas the knowledge that farmers have and ways to explore it ...
Bregt, A.K., Bruin, S., de, Heijting, S.
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Spatial knowledge for risks prevention and mitigation
TeMA: Journal of Land Use, Mobility and Environment, 2021 The scientific research described in this paper concerns the theme of Civil Protection Planning at Regional level and Disaster Risk Management. In particular, it concerns the definition and experimentation of a particular model of basic Knowledge System.
Donato Di Ludovico +2 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Cybergeo, 1997 Reading is a common living experience; it is source of dualism : travel through a linear oriented structure as well as a graph’s projection on an imaginary screen. It is mostly automatic, unconscious.
Hervé Gazel
doaj +1 more source
Movement Ecology, 2020 Background Animals respond to environmental variation by changing their movement in a multifaceted way. Recent advancements in biologging increasingly allow for detailed measurements of the multifaceted nature of movement, from descriptors of animal ...
J. A. J. Eikelboom +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Spatial Knowledge and Behaviour
, 2017 Using spatial media to understand, navigate and act on the world is an integral element in being a connected, technology-using individual. Apple users discovered just how critical spatial media are to their everyday life when updating their mobile devices to the iOS6 operating system on 19 September 2012.
Evans, Leighton, Perng, Sung-Yueh
openaire +3 more sources