Results 81 to 90 of about 357,223 (321)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Rapid Fabrication of Hydrogel Microstructures Using UV-Induced Projection Printing

open access: yesMicromachines, 2015
Fabrication of hydrogel microstructures has attracted considerable attention. A large number of applications, such as fabricating tissue engineering scaffolds, delivering drugs to diseased tissue, and constructing extracellular matrix for studying cell ...
Wenguang Yang   +4 more
doaj   +1 more source

Waveguide Panel Display Using Electromechanical Spatial Modulators [PDF]

open access: yes, 1998
A novel micro‐electro‐mechanical system (MEMS) approach in waveguide panel displays (WPD) is described. High efficiency electromechanical spatial modulators, based on the use of frustrated total internal reflection, were demonstrated.
Gulari, Erdogan, Zhou, Xiaochuan
core   +1 more source

Phase-only transmissive spatial light modulator based on tunable dielectric metasurface [PDF]

open access: yesScience, 2019
Dynamic metasurfaces Nanostructured metasurfaces can function as many passive optical elements. Now, S.-Q. Li et al. demonstrate that metasurfaces can be combined with liquid crystals to provide active control over light beams.
Shiqiang Li   +5 more
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Single pixel imaging at megahertz switching rates via cyclic Hadamard masks

open access: yesNature Communications, 2021
Imaging rates in single-pixel imaging has been limited by the dependence on configurable spatial light modulators. Here, the authors use cyclic Hadamard patterns coded onto a spinning mask to demonstrate dynamic imaging with rates up to 72 frames per ...
Evgeny Hahamovich   +3 more
doaj   +1 more source

Realization of an atomically thin mirror using monolayer MoSe2

open access: yes, 2017
Advent of new materials such as van der Waals heterostructures, propels new research directions in condensed matter physics and enables development of novel devices with unique functionalities.
Back, Patrick   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

High-Flexibility Control of Structured Light with Combined Adaptive Optical Systems

open access: yesPhotonics, 2022
Combining the specific advantages of high-resolution liquid-crystal-on-silicon spatial light modulators (LCoS-SLMs) and reflective or refractive micro-electro-mechanical systems (MEMS) presents new prospects for the generation of structured light fields.
Ruediger Grunwald   +6 more
doaj   +1 more source

Particlelike scattering states in a microwave cavity

open access: yes, 2017
We realize scattering states in a lossy and chaotic two-dimensional microwave cavity which follow bundles of classical particle trajectories. To generate such particlelike scattering states we measure the system's transmission matrix and apply an adapted
Ambichl, Philipp   +4 more
core   +3 more sources

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