Results 101 to 110 of about 3,938,305 (341)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
PERUBAHAN SPASIAL TUTUPAN LAHAN DI DAS CITARUM HULU
Journal of Natural Resources and Environmental Management, 2018 Land cover is one of factors which is important in watershed management. The changes of land cover in a watershed can affect the hydrology abstraction. Land cover of upstream Citarum watershed is potentially changes.
Sri Malahayati Yusuf
doaj +1 more source
Quasi-cycles in a spatial predator-prey model
, 2008 We show that spatial models of simple predator-prey interactions predict that predator and prey numbers oscillate in time and space. These oscillations are not seen in the deterministic versions of the models, but are due to stochastic fluctuations about
Lugo, Carlos A., McKane, Alan J.
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Phase transition in a spatial Lotka-Volterra model
, 2000 Spatial evolution is investigated in a simulated system of nine competing and mutating bacterium strains, which mimics the biochemical war among bacteria capable of producing two different bacteriocins (toxins) at most.
A.J. Lotka +17 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fire Data as Proxy for Anthropogenic Landscape Change in the Yucatán
Land, 2017 Fire is one of the earliest and most common tools used by humans to modify the earth surface. Landscapes in the Yucatán Peninsula are composed of a mosaic of old growth subtropical forest, secondary vegetation, grasslands, and agricultural land that ...
Marco Millones +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Shaping the Space: A Role for the Hippocampus in Mental Imagery Formation
VisionMental imagery is claimed to underlie a host of abilities, such as episodic memory, working memory, and decision-making. A popular view holds that mental imagery relies on the perceptual system and that it can be said to be ‘vision in reverse’.
Andrea Blomkvist
doaj +1 more source