Results 31 to 40 of about 59,208 (264)

A consistent map in the medial entorhinal cortex supports spatial memory

open access: yesNature Communications
The medial entorhinal cortex (MEC) is hypothesized to function as a cognitive map for memory-guided navigation. How this map develops during learning and influences memory remains unclear. By imaging MEC calcium dynamics while mice successfully learned a
Taylor J. Malone   +12 more
doaj   +1 more source

An Effective GNSS/PDR Fusion Positioning Algorithm on Smartphones for Challenging Scenarios

open access: yesSensors
The location-based smartphone service brings new development opportunities for seamless indoor/outdoor positioning. However, in complex scenarios such as cities, tunnels, overpasses, forests, etc., using only GNSS on smartphones cannot provide stable and
Jingkui Zhang   +4 more
doaj   +1 more source

Spatial Knowledge Acquisition for Pedestrian Navigation: A Comparative Study between Smartphones and AR Glasses

open access: yesInformation, 2023
Smartphone map-based pedestrian navigation is known to have a negative effect on the long-term acquisition of spatial knowledge and memorisation of landmarks.
Aymen Lakehal   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Spatial navigation ability is associated with the assessment of smoothness of driving during changing lanes in older drivers

open access: yesJournal of Physiological Anthropology, 2020
Background Age-related changes affect driving ability, including the smoothness of driving. This operation requires the use of both allocentric strategies (based on world-centered representations) and egocentric strategies (based on self-centered ...
Masafumi Kunishige   +5 more
doaj   +1 more source

Impact of Navigation Aid and Spatial Ability Skills on Wayfinding Performance and Workload in Indoor-Outdoor Campus Navigation: Challenges and Design

open access: yesApplied Sciences, 2023
Wayfinding is important for everyone on a university campus to understand where they are and get to where they want to go to attend a meeting or a class.
Rabail Tahir, John Krogstie
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Neural Approach to Coordinate Transformation for LiDAR–Camera Data Fusion in Coastal Observation

open access: yesSensors
The paper presents research related to coastal observation using a camera and LiDAR (Light Detection and Ranging) mounted on an unmanned surface vehicle (USV).
Ilona Garczyńska-Cyprysiak   +2 more
doaj   +1 more source

Hyperspectral Features of Oil-Polluted Sea Ice and the Response to the Contamination Area Fraction

open access: yesSensors, 2018
Researchers have studied oil spills in open waters using remote sensors, but few have focused on extracting reflectance features of oil pollution on sea ice.
Bingxin Liu   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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