Results 41 to 50 of about 59,208 (264)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Portable Side-Scan Sonar System for Acoustic Remote Sensing of Ultra-Shallow Seafloor: Design and Field Validation

Remote Sensing
Ultra-shallow and confined water environments are challenging to survey with conventional towed side-scan sonar (SSS) due to limited access and positioning uncertainties.
Artur Grządziel, Filip Grządziel
doaj   +1 more source

Spatial navigation – a unique window into physiological and pathological aging

Frontiers in Aging Neuroscience, 2012
Spatial navigation is a skill of determining and maintaining a trajectory from one place to another. Mild progressive decline of spatial navigation develops gradually during the course of physiological ageing.
Ivana eGazova, Ivana eGazova, Kamil eVlcek, Kamil eVlcek, Jan eLaczo, Jan eLaczo, Zuzana eNedelska, Zuzana eNedelska, Eva eHyncicova, Ivana eMokrisova, Katerina eSheardova, Jakub eHort, Jakub eHort   +12 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Eye-Movements During Navigation in a Virtual Environment: Sex Differences and Relationship to Sex Hormones

Frontiers in Neuroscience, 2022
Sex differences in spatial navigation have been related to different navigation strategies. For example, women are more likely to utilize local landmark-information in the environment compared to men.
TiAnni Harris, Johanna Hagg, Belinda Pletzer   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Age-related differences and cognitive correlates of Self-reported and Direct navigation performance: the effect of real and virtual test conditions manipulation

Frontiers in Psychology, 2016
The present study investigated the effect of aging on direct navigation measures and self-reported ones according to the real-virtual test manipulation.
Mathieu eTaillade, Bernard eN'Kaoua, Hélène eSauzéon, Hélène eSauzéon   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

An Improved Model for Detecting Heavy Precipitation Using GNSS-Derived Zenith Total Delay Measurements

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021
In recent years, precipitable water vapor has been widely used in heavy precipitation prediction, which is obtained from a conversion of the zenith total delay (ZTD) of the GNSS signal.
Haobo Li, Xiaoming Wang, Suqin Wu, Kefei Zhang, Xialan Chen, Jinglei Zhang, Cong Qiu, Shaotian Zhang, Li Li   +8 more
doaj   +1 more source