Results 61 to 70 of about 74,091 (312)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Evidence for a shift from true place navigation to directional responding in one variant of the morris water task.

, 2009
Previous work from our laboratory has demonstrated that rats display a preference for directional responding over place navigation in a wide range of procedural variants of the Morris water task.
Redhead, Edward S., Candelaria, Felicha T., Hamilton, Derek A., Akers, Katherine G., Rice, James P., Johnson, Travis E.   +5 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

The relative influence of place and direction in the Morris water task

, 2008
The present study evaluated the generality of directional responding (Hamilton, Akers, Weisend, & Sutherland, 2007) in the Morris water task and attempted to identify methods that would yield a preference for navigation to the precise spatial ...
Sutherland, R.J., Candelaria, F.T., Weisend, M.P., Rice, J.P., Johnson, T.E., Akers, G.K., Redhead, E.S., Hamilton, D.A.   +7 more
core   +1 more source

GpsTunes: controlling navigation via audio feedback [PDF]

, 2005
We combine the functionality of a mobile Global Positioning System (GPS) with that of an MP3 player, implemented on a PocketPC, to produce a handheld system capable of guiding a user to their desired target location via continuously adapted music ...
Strachan, S., Murray-Smith, R., Sile O'Modhrain, Eslambolchilar, P., Steven Strachan, Hughes, S., Roderick Murray-Smith, O'Modhrain, S., Parisa Eslambolchilar, Stephen Hughes   +9 more
core   +1 more source

Spatial representation for pragmatic navigation [PDF]

, 1997
This paper focuses upon features of two-dimensional space that facilitate and/or obstruct travel through it. Three kinds of facilitators and four kinds of obstructers are identified. For each one, learning algorithms and navigational applications are proposed. The program described here simulates a robot that learns such features as it encounters them,
openaire   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Implicit Measures of Lostness and Success in Web Navigation [PDF]

, 2007
In two studies, we investigated the ability of a variety of structural and temporal measures computed from a web navigation path to predict lostness and task success. The user’s task was to find requested target information on specified websites. The web
Ian Spence, Gwizdka, Jacek, Spence, Ian, Jacek Gwizdka   +3 more
core  

Solving the detour problem in navigation: a model of prefrontal and hippocampal interactions.

, 2015
Adapting behavior to accommodate changes in the environment is an important function of the nervous system. A universal problem for motile animals is the discovery that a learned route is blocked and a detour is required.
Spiers, HJ, Sam J Gilbert, Gilbert, SJ, Hugo J Spiers, Hugo J. Spiers, Sam J. Gilbert   +5 more
core   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source