Results 111 to 120 of about 364,113 (314)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, Volume 16, Issue 7, Page 1271-1292, July 2026.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Spatial ecology of peatland ecosystems: Spatial self-organization and catastrophic shifts in bogs

open access: yes, 2004
Positive feedback interactions, as between plants and their abiotic environment, may have the consequence that an ecosystem has alternate stable equilibrium states.
Eppinga, M.B.
core  

On the Determinants of Human Spatial Organization [PDF]

open access: yes, 2020
Humans routinely organize and reorganize their environments, such as keeping one’s bookshelves tidy or placing important documents in obvious locations to avoid forgetting about them. Spatial organization is widely thought to reduce both the physical and
Zhu, Mona
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Spatial Development Strategy: A View from the Concepts of Spatial Organization in the Economy

open access: yes, 2018
The author has conducted a comparative analysis of the contents of the Strategy of Spatial Development of the Russian Federation till 2025 and the theoretical concepts, on which such strategy has to be founded.
Pavel Aleksandrovich Minakir
core   +1 more source

Evasion of tipping in complex systems through spatial pattern formation [PDF]

open access: yes, 2021
The concept of tipping points and critical transitions helps inform our understanding of the catastrophic effects that global change may have on ecosystems, Earth system components, and the whole Earth system.
Swarnendu, Banerjee   +5 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, Volume 16, Issue 7, Page 1305-1313, July 2026.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Spatial cognition, memory organization and creativity in planning and architecture

open access: yes, 2012
The significances and the roles of creativity and memories in spatial organizations are boosting the increasing attention of scholars and professionals. In cognition-oriented spatial studies, creativity is gradually considered as a normal character of an
CAMARDA, Domenico, BORRI, Dino
core  

Spatial organization of multi-enzyme biocatalytic cascades

open access: yes, 2017
Multi-enzyme cascades provide a wealth of valuable chemicals. Efficiency of reaction schemes can be improved by spatial organization of biocatalysts.
G. Zhang   +3 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, Volume 16, Issue 7, Page 1314-1327, July 2026.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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