Results 31 to 40 of about 8,729 (264)

CONTROLLING THE MOVEMENT OF HEXACOPTER ALONG THE INTENDED ROUTE WITH ENGINE FAILURE [PDF]

Scientific Journal of Silesian University of Technology. Series Transport
This article investigates the issue of controlling the movement of a hexacopter-type unmanned aerial vehicle around a route. The movement of the hexacopter is modeled as the motion of a rigid body, taking into account gravitational forces and aerodynamic
Gulush NABADOVA
doaj   +1 more source

Spatial Recognition Memory: Differential Brain Strategic Activation According to Sex

Frontiers in Behavioral Neuroscience, 2021
Human spatial memory research has significantly progressed since the development of computerized tasks, with many studies examining sex-related performances. However, few studies explore the underlying electrophysiological correlates according to sex. In
Joaquín Castillo, Joaquín Castillo, Isabel Carmona, Isabel Carmona, Sean Commins, Sergio Fernández, Sergio Fernández, Juan José Ortells, Juan José Ortells, José Manuel Cimadevilla, José Manuel Cimadevilla   +10 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Patients with Parkinson’s Disease Show Alteration in their Visuospatial Abilities and in their Egocentric and Allocentric Spatial Orientation Measured by Card Placing Tests

Journal of Parkinson’s Disease, 2020
Background: Visuospatial skills are impaired in Parkinson’s disease (PD). Other related skills exist, such as spatial orientation have been poorly studied.
Cristina Fernandez-Baizan, M. Paula Fernandez Garcia, Elena Diaz-Caceres, Manuel Menendez-Gonzalez, Jorge L. Arias, Marta Mendez   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Multiple-Choice Maze-like Spatial Navigation Task for Humans Implemented in a Real-Space, Multipurpose Circular Arena

Applied Sciences, 2022
Spatial navigation is a key aspect of human behavior and it is still not completely understood. A number of experimental approaches exist, although most of the published data in the last decades have relied on virtual maze on-screen simulation or not ...
Pablo Muela, Elisa Cintado, Patricia Tezanos, Benjamín Fernández-García, Cristina Tomás-Zapico, Eduardo Iglesias-Gutiérrez, Angel Enrique Díaz Martínez, Ray G. Butler, Victor Cuadrado-Peñafiel, Ricardo De la Vega, Vanesa Soto-León, Antonio Oliviero, Laura López-Mascaraque, José Luis Trejo   +13 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Assisted Tea Leaf Picking: The Design and Simulation of a 6-DOF Stewart Parallel Lifting Platform

Agronomy
The 6-DOF Stewart parallel elevation platform serves as the platform for mounting the tea-picking robotic arm, significantly impacting the operational scope, velocity, and harvesting precision of the robotic arm.
Zejun Wang, Chunhua Yang, Raoqiong Che, Hongxu Li, Yaping Chen, Lijiao Chen, Wenxia Yuan, Fang Yang, Juan Tian, Baijuan Wang   +9 more
doaj   +1 more source