Results 41 to 50 of about 235,967 (261)
Applied Sciences, 2022 Spatial navigation is a key aspect of human behavior and it is still not completely understood. A number of experimental approaches exist, although most of the published data in the last decades have relied on virtual maze on-screen simulation or not ...
Pablo Muela +13 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Brain Sciences, 2020 Traditionally, the medial temporal lobe has been considered a key brain region for spatial memory. Nevertheless, executive functions, such as working memory, also play an important role in complex behaviors, such as spatial navigation.
Joaquín Castillo Escamilla +5 more
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Revista de Investigación e Innovación en Ciencias de la Salud, 2023 Background. Working memory-based spatial cognition has attracted the attention of the scientific community in navigation and reorientation projects.
Chrysanthi Basdekidou +3 more
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
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SPATIAL ORIENTATION BY QUANTUM TELEPATHY
International Journal of Quantum Information, 2007 We implemented the protocol of entanglement assisted orientation in the space proposed by Brukner et al. (quant-ph/0509123). We used min-max principle to evaluate the optimal entangled state and the optimal direction of polarization measurements which violate the classical bound.
Bovino, F +3 more
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Multisensory integration in spatial orientation [PDF]
Current Opinion in Neurobiology, 1999 Recent psychophysical studies on normal subjects, as well as brain imaging studies, have revised the concepts concerning the mechanisms underlying spatial orientation during navigation tasks. The emphasis has been put on internal models that allow the prediction of a planned trajectory and are essential in the steering of locomotion.
Berthoz, Alain, Viaud-Delmon, Isabelle
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