Results 91 to 100 of about 719,902 (313)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Exploring the spatial pattern of historic Chinese towns and cities: A syntactical approach
, 2021 This study explores the spatial pattern of Historic Chinese Towns and Cities (HCTC) by using a syntactic approach. The HCTC is an important element of the built environment and exhibits a variety of unique spatial characteristics.
Liao, P +7 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Monoclonal antibodies reveal changes in predator efficiency with prey spatial pattern
, 2008 Spatially explicit predator-prey interactions can alter the predatory potential of natural enemies augmented through conservation biological control.
Kennedy, P. J. +13 more
core +1 more source
Cell Sorting daring Pattern Formation in Dictyostelium [PDF]
, 1981 Formation of the prestalk-prespore pattern in Dictyostelium was investigated in slugs and submerged clumps of cells. Prestalk and prespore cells were identified by staining with vital dyes, which are shown to be stable cell markers.
Sternfeld, John, David, Charles N.
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Mapping uneven spatial pattern in Tehran. Experimenting with GIS technologies
, 2015 Mapping Uneven Spatial Pattern in Tehran. Experimenting with GIS TechnologiesMapping Uneven Spatial Pattern in Tehran.
RABIEI DASTJERDI, HAMIDREZA
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Regular pattern formation in real ecosystems
, 2008 Localized ecological interactions can generate striking large-scale spatial patterns in ecosystems through spatial self-organization. Possible mechanisms include oscillating consumer–resource interactions, localized disturbance-recovery processes and ...
Koppel, Johan van de, +5 more
core +1 more source