Results 71 to 80 of about 719,902 (313)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Studying Land Use and Land Cover Spatial Patterns Distribution in Crete, Greece with Means of Satellite Remote Sensing

open access: yesProceedings, 2020
Multi-temporal Land use and Land cover (LULC) monitoring is a crucial parameter for assessing an area’s landscape ecology regime. LULC changes can be effectively used to describe dynamics of both urban or rural environments and vegetation patterns as an ...
Dimitrios D. Alexakis   +1 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Testing for similarity in area‐based spatial patterns: Alternative methods to Andresen's spatial point pattern test

open access: yes, 2018
Andresen's spatial point pattern test (SPPT) compares two spatial point patterns on defined areal units; it identifies areas where the spatial point patterns diverge and aggregates these local (dis)similarities to one global measure.
Andresen, Martin A   +5 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Measures of Spatial Pattern for Counts

open access: yesEcology, 1998
SADIE (Spatial Analysis by Distance IndicEs) is a new methodology to detect and measure the degree of nonrandomness in the two-dimensional spatial patterns of populations. It applies the same principles to data in the form of maps as to data in the form of counts at specified locations, but with different techniques.
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Spatial analysis for colon biopsy classification from hyperspectral imagery [PDF]

open access: yes, 2008
Automatic classification of histology images, the objective of our research, is aimed at supporting the pathologists in their diagnosis. In this paper, we present a comparative study between 3D spectral/spatial analysis (SSA) and 2D spatial analysis (SA ...
Rajpoot, Nasir M. (Nasir Mahmood)   +1 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Regionalization of landscape pattern indices using multivariate cluster analysis

open access: yes, 2014
This project was funded by the Government of Canada through the Mountain Pine Beetle Program, a six-year, $40 million program administered by Natural Resources Canada, Canadian Forest Service.
Wulder, M.A.   +2 more
core   +1 more source

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