Results 101 to 110 of about 24,126 (306)
Real-Time Spatial Queries for Moving Objects Using Storm Topology
With the rapid development of mobile data acquisition technology, the volume of available spatial data is growing at an increasingly fast pace. The real-time processing of big spatial data has become a research frontier in the field of Geographic ...
Feng Zhang +6 more
doaj +1 more source
CONTINUOUS MULTIQUERIES K-DOMINANT SKYLINE ON ROAD NETWORK
The increasing use of mobile devices makes spatial data worthy of consideration. To get maximum results, users often look for the best from a collection of objects. Among the algorithms that can be used is the skyline query.
Syukron Rifail Muttaqi +1 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Development and evaluation of a geographic information retrieval system using fine grained toponyms
Geographic information retrieval (GIR) is concerned with returning information in response to an information need, typically expressed in terms of a thematic and spatial component linked by a spatial relationship.
Damien Palacio +2 more
doaj +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
EVALUATING SPATIAL QUERIES OVER DECLUSTERED SPATIAL DATA [PDF]
Due to the large volumes of spatial data, data is stored on clusters of machines that inter-communicate to achieve a task. In such distributed environment; communicating intermediate results among computing nodes dominates execution time. Communication
Eslam A Almorshdy (6832553)
core +3 more sources
Efficient 3D Spatial Queries for Complex Objects. [PDF]
Teng D, Liang Y, Vo H, Kong J, Wang F.
europepmc +1 more source
Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source

