Results 81 to 90 of about 24,126 (306)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Adaptive Distributed Indexing [PDF]

open access: yes, 2008
Sensor networks have opened new horizons and opportunities for a variety of environmental monitoring, surveillance and healthcare applications. One of the major tasks of sensor networks is the distributed collection and processing of sensor readings over
For Spatial Queries   +2 more
core  

Genomes as geography: using GIS technology to build interactive genome feature maps

open access: yesBMC Bioinformatics, 2006
Background Many commonly used genome browsers display sequence annotations and related attributes as horizontal data tracks that can be toggled on and off according to user preferences.
Beard M Kate   +3 more
doaj   +1 more source

Top-k Spatial Preference Queries [PDF]

open access: yes2007 IEEE 23rd International Conference on Data Engineering, 2007
A spatial preference query ranks objects based on the qualities of features in their spatial neighborhood. For example, consider a real estate agency office that holds a database with available flats for lease. A customer may want to rank the flats with respect to the appropriateness of their location, defined after aggregating the qualities of other ...
Man Lung Yiu   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Efficient Analysis in Multimedia Databases [PDF]

open access: yes, 2006
The rapid progress of digital technology has led to a situation where computers have become ubiquitous tools. Now we can find them in almost every environment, be it industrial or even private.
Peter Kunath, Kunath, Peter
core  

LocationSpark: In-memory Distributed Spatial Query Processing and Optimization

open access: yesFrontiers in Big Data, 2020
Due to the ubiquity of spatial data applications and the large amounts of spatial data that these applications generate and process, there is a pressing need for scalable spatial query processing.
Mingjie Tang   +5 more
doaj   +1 more source

Spatial queries with two kNN predicates [PDF]

open access: yesProceedings of the VLDB Endowment, 2012
The widespread use of location-aware devices has led to countless location-based services in which a user query can be arbitrarily complex, i.e., one that embeds multiple spatial selection and join predicates. Amongst these predicates, the k -Nearest-Neighbor ( k NN) predicate stands as one ...
Aly, Ahmed   +2 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Querying spatial data by dominators in neighborhood [PDF]

open access: yesInformation Systems, 2018
Spatial objects in reality are often associated with geographic locations (e.g., longitude and latitude) as well as multiple quality attributes. Quality attributes make it possible to compare spatial objects according to the dominance concept. Specifically, an object pi is said to dominate another object pj if pi is no worse than pj on all quality ...
Hua Lu 0001, Man Lung Yiu, Xike Xie
openaire   +2 more sources

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