Results 61 to 70 of about 19,086 (267)
Querying spatial data by dominators in neighborhood [PDF]
Information Systems, 2018 Spatial objects in reality are often associated with geographic locations (e.g., longitude and latitude) as well as multiple quality attributes. Quality attributes make it possible to compare spatial objects according to the dominance concept. Specifically, an object pi is said to dominate another object pj if pi is no worse than pj on all quality ...
Hua Lu 0001, Man Lung Yiu, Xike Xie
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Construct Trip Graphs by Using Taxi Trajectory Data
Data Science and Engineering, 2023 The trip graph, which can model the residents’ taxi demands, consists of vertices used to indicate trips and edges used to indicate the follow-up relationships between trips. A trip $$v_j$$ v j is a tight follow-up trip of another trip $$v_i$$ v i , if a
Hao Yu +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Real-Time Spatial Queries for Moving Objects Using Storm Topology
ISPRS International Journal of Geo-Information, 2016 With the rapid development of mobile data acquisition technology, the volume of available spatial data is growing at an increasingly fast pace. The real-time processing of big spatial data has become a research frontier in the field of Geographic ...
Feng Zhang +6 more
doaj +1 more source
CONTINUOUS MULTIQUERIES K-DOMINANT SKYLINE ON ROAD NETWORK
JUTI: Jurnal Ilmiah Teknologi Informasi, 2020 The increasing use of mobile devices makes spatial data worthy of consideration. To get maximum results, users often look for the best from a collection of objects. Among the algorithms that can be used is the skyline query.
Syukron Rifail Muttaqi +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source