Results 61 to 70 of about 24,126 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Dynamic Data Structure to Efficiently Find the Points below a Line and Estimate Their Number

open access: yesISPRS International Journal of Geo-Information, 2017
A basic question in computational geometry is how to find the relationship between a set of points and a line in a real plane. In this paper, we present multidimensional data structures for N points that allow answering the following queries for any ...
Bart Kuijpers, Peter Z. Revesz
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Location and Intent Privacy Preservation for Spatial Range Queries in a Mobile Network

open access: yesIEEE Access
Location-based services (LBSs) in a mobile network environment that provide personalized and timely information to users entail privacy concerns due to the leakage of user locations to adversaries.
Shadaab Siddiqie   +2 more
doaj   +1 more source

Mobility Data Warehouses

open access: yesISPRS International Journal of Geo-Information, 2019
The interest in mobility data analysis has grown dramatically with the wide availability of devices that track the position of moving objects. Mobility analysis can be applied, for example, to analyze traffic flows.
Alejandro Vaisman, Esteban Zimányi
doaj   +1 more source

On Nearby-Fit Spatial Keyword Queries [PDF]

open access: yesIEEE Transactions on Knowledge and Data Engineering, 2020
Geo-textual data is ubiquitous nowadays, where each object has a location and is associated with some keywords. Many types of queries based on geo-textual data, termed as spatial keyword queries , have been proposed, and are to find optimal object(s) in terms of both its (their) location(s) and keywords.
Victor Junqiu Wei   +3 more
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The combination of spatial access methods and computational geometry in geographic database systems [PDF]

open access: yes, 1991
Geographic database systems, known as geographic information systems (GISs) particularly among non-computer scientists, are one of the most important applications of the very active research area named spatial database systems. Consequently following the
Kriegel, Hans-Peter   +5 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Impact of Global Clustering on Spatial Database Systems [PDF]

open access: yes, 1994
Global clustering has rarely been investigated in the area of spatial database systems although dramatic performance improvements can be achieved by using suitable techniques.
Kriegel, Hans-Peter   +3 more
core  

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