Results 61 to 70 of about 22,408 (308)

IB-CBB: an improved spatial index considering intersection based on clipped bounding boxes

Annals of GIS
Efficiently querying multiple spatial datasets is a challenging task in geoscience. The majority of spatial processing techniques use minimum bounding box (MBB) to approximate neighbouring spatial objects and and place them adjacent in the spatial index.
Wei Xiong, Ye Wu, Jingzhi Cao, Ruiqing Li   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Top-k Spatial Preference Queries in Directed Road Networks

ISPRS International Journal of Geo-Information, 2016
Top-k spatial preference queries rank objects based on the score of feature objects in their spatial neighborhood. Top-k preference queries are crucial for a wide range of location based services such as hotel browsing and apartment searching.
Muhammad Attique, Hyung-Ju Cho, Rize Jin, Tae-Sun Chung   +3 more
doaj   +1 more source

A SPEED-UP GEOMETRIC CHANGE DETECTION ALGORITHM FOR VECTOR SURFACE FEATURE SET [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2018
At present, most of the researches on geometric change detection of vector data, they store the change detection results in the database, so they pay more attention to the accuracy of results, but not to the speed of processing.
L. Zhu, C. Li, L. Liu, J. Shen, L. Yang, Z. Liu   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Distance-Constraint k-Nearest Neighbor Searching in Mobile Sensor Networks

Sensors, 2015
The κ -Nearest Neighbors ( κNN) query is an important spatial query in mobile sensor networks. In this work we extend κNN to include a distance constraint, calling it a l-distant κ-nearest-neighbors ( l ...
Yongkoo Han, Kisung Park, Jihye Hong, Noor Ulamin, Young-Koo Lee   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Error-bounded and Number-bounded Approximate Spatial Query for Interactive Visualization

Open Geosciences, 2018
In the big data era, an enormous amount of spatial and spatiotemporal data are generated every day. However, spatial query result sets that satisfy a query condition are very large, sometimes over hundreds or thousands of terabytes.
Qiu Agen, Zhang Zhiran, Qian Xinlin, He Wangjun   +3 more
doaj   +1 more source

Probabilistic CkNN Queries of Uncertain Data in Large Road Networks

IEEE Access, 2016
Continuous k-nearest neighbor (CkNN) query processing is an important issue in spatial temporal databases. In real-world scenarios, query clients and data objects may move with uncertain speeds on the road networks, which makes retrieving the exact CkNN ...
Yanhong Li, Rongbo Zhu, Guohui Li, Lihchyun Shu, Changyin Luo   +4 more
doaj   +1 more source