Results 41 to 50 of about 23,439 (262)

SGIR-Tree: Integrating R-Tree Spatial Indexing as Subgraphs in Graph Database Management Systems

ISPRS International Journal of Geo-Information
Efficient spatial query processing in Graph Database Management Systems (GDBMSs) has become increasingly important owing to the prevalence of spatial graph data.
Juyoung Kim, Seoyoung Hong, Seungchan Jeong, Seula Park, Kiyun Yu   +4 more
doaj   +1 more source

INDEXING AND QUERY PROCESSING TECHNIQUES IN SPATIO-TEMPORAL DATA [PDF]

ICTACT Journal on Soft Computing, 2016
Indexing and query processing is an emerging research field in spatio - temporal data. Most of the real-time applications such as location based services, fleet management, traffic prediction and radio frequency identification and sensor networks are ...
A John, M Sugumaran, R S Rajesh
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Towards Parallel Spatial Query Processing for Big Spatial Data [PDF]

2012 IEEE 26th International Parallel and Distributed Processing Symposium Workshops & PhD Forum, 2012
In recent years, spatial applications have become more and more important in both scientific research and industry. Spatial query processing is the fundamental functioning component to support spatial applications. However, the state-of-the-art techniques of spatial query processing are facing significant challenges as the data expand and user accesses
Yunqin Zhong, Jizhong Han, Tieying Zhang, Zhenhua Li 0001, Jinyun Fang, Guihai Chen   +5 more
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A KNN Dynamic Extended Query Strategy Based on GPU [PDF]

Jisuanji gongcheng, 2018
Traditional Graphics Processing Unit(GPU) executing PGrid index K-Nearest Neighbor(KNN) query method has problems such as large query granularity,redundant calculation,and unstable performance.Therefore,facing spatial KNN relation queries,a KNN query ...
TANG Jia,GONG Yili,LI Wenhai
doaj   +1 more source

Query Processing of Geosocial Data in Location-Based Social Networks

ISPRS International Journal of Geo-Information, 2021
The increasing use of social media and the recent advances in geo-positioning technologies have produced a great amount of geosocial data, consisting of spatial, textual, and social information, to be managed and queried.
Arianna D’Ulizia, Patrizia Grifoni, Fernando Ferri   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source