Results 21 to 30 of about 1,914 (212)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Abstract spatial reasoning as an autistic strength.

PLoS ONE, 2013
Autistic individuals typically excel on spatial tests that measure abstract reasoning, such as the Block Design subtest on intelligence test batteries and the Raven's Progressive Matrices nonverbal test of intelligence.
Jennifer L Stevenson, Morton Ann Gernsbacher   +1 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Spatial Reasoning and Its Contribution to Mathematical Performance Across Different Content Domains: Evidence from Chinese Students

Journal of Intelligence
Recent studies have provided convincing evidence highlighting the strong relationship between spatial reasoning and mathematical performance. However, there is a limited body of research exploring the contributions of different spatial reasoning ...
Tianshu Xu, Siyu Sun, Qiping Kong
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Preschoolers’ Perceptual Analogical Reasoning and Map Reading: A Preliminary Study on the Mediating Effect of Spatial Language

Children, 2023
Reading and interpreting a map represents an essential part of daily life, enabling appropriate orientation and navigation through space. Based on the idea that perceptual analogical reasoning is critical in aligning the spatial structure of the map with
Marco Giancola, Maria Chiara Pino, Valentina Riccio, Laura Piccardi, Simonetta D’Amico   +4 more
doaj   +1 more source

Qualitative Spatial Reasoning Extracting and Reasoning with Spatial Aggregates.

AI Mag., 2003
Reasoning about spatial data is a key task in many applications, including geographic information systems, meteorological and fluid-flow analysis, computer-aided design, and protein structure databases. Such applications often require the identifi- cation and manipulation of qualitative spatial representations, for example, to detect whether one object
Bailey-Kellogg, Chris, Zhao, Feng
openaire   +2 more sources

Algorithms for Hierarchical Spatial Reasoning [PDF]

GeoInformatica, 1997
In several applications, there is the need to reason about spatial relations using multiple local frames of reference that are hierarchically organized. This paper focuses on hierarchical reasoning about direction relations, a special class of spatial relations that describe order in space (e.g., north or northeast).
Papadias, D., Egenhofer, M.J.
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source