Results 31 to 40 of about 1,914 (212)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Role of Spatial Anxiety in The Relationship Between Mathematics Anxiety and Spatial Reasoning

Journal on Efficiency and Responsibility in Education and Science
This study explored the connection between mathematics anxiety and spatial reasoning, examining potential mediating and moderating effects of spatial anxiety, as well as the roles of grade level and gender. A cross-sectional survey was conducted with 477
Yoppy Wahyu Purnomo, Firda Nur Fadhilah, Ucu Sumusiasih, Rina Dyah Rahmawati, Yeni Fitriya   +4 more
doaj   +1 more source

Schoolchildren's Spatial Reasoning.

, 2020
sponsorship: KU Leuven ...
Demiddele, Kevin, Heyman, Tom, Schaeken, Walter   +2 more
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Analysis of spatial reasoning ability in solving geometric transformation problems

Jurnal Math Educator Nusantara: Wahana Publikasi Karya Tulis Ilmiah di Bidang Pendidikan Matematika
Spatial reasoning ability significantly affects mathematics learning in the area of geometric transformations. However, students’ spatial reasoning ability is still underdeveloped. This study focused on analyzing students’ spatial reasoning ability while
Erni Puji Astuti, Reza Septia Handayani, Karisma Nurul Ngulia, Dwi Lestari, Debi Saktiyani, Sintya Linggar Pradana   +5 more
doaj   +1 more source

Spatial reasoning in Tenejapan Mayans [PDF]

Cognition, 2011
Language communities differ in their stock of reference frames (coordinate systems for specifying locations and directions). English typically uses egocentrically-defined axes (e.g., "left-right"), especially when describing small-scale relationships.
Peggy, Li, Linda, Abarbanell, Lila, Gleitman, Anna, Papafragou   +3 more
openaire   +2 more sources

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Spatial Visualization Supports Students’ Math: Mechanisms for Spatial Transfer

Journal of Intelligence, 2023
The present study conducted a randomized control trial to assess the efficacy of two spatial intervention programs aimed to improve Grade 4 (N = 287) students’ spatial visualization skills and math performance.
Tom Lowrie, Tracy Logan
doaj   +1 more source

An ontology for linear spatial reasoning [PDF]

, 1996
An ontology for spatial reasoning based on a tesseral representation of space is presented. The principal advantage offered is that the representation has the effect of linearising multi-dimensional space while still supporting translation through the space in any direction and through any number of dimensions.
Frans Coenen, Bridget Beattie, Trevor J. M. Bench-Capon, Michael J. R. Shave, B. M. Diaz   +4 more
openaire   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source