Results 51 to 60 of about 8,060,684 (303)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Multi-scale data storage schemes for spatial information systems [PDF]
, 2012 This thesis documents a research project that has led to the design and prototype implementation of several data storage schemes suited to the efficient multi-scale representation of integrated spatial data.
Ware, John Mark
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Frontiers in Marine Science, 2019 Coral reefs are complex and biodiverse ecosystems that are undergoing significant change. Understanding reef composition and biodiversity at multiple spatial scales is necessary to track both large-scale and more subtle ecosystem changes. The Jardines de
Leslie Hernández-Fernández +5 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Knowledge and Management of Aquatic Ecosystems, 2011 We report an investigation aimed at improving the understanding of the relationships between hydromorphology and land cover, and in particular aimed at identifying the spatial scale on which land cover patterns best account for the ...
Tudesque L., Gevrey M., Lek S.
doaj +1 more source
Variable ranking and selection with random forest for unbalanced data
Environmental Data Science, 2022 When one or several classes are much less prevalent than another class (unbalanced data), class error rates and variable importances of the machine learning algorithm random forest can be biased, particularly when sample sizes are smaller, imbalance ...
Ute Bradter +5 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
International Journal of Digital Earth, 2023 The combination of spatial distribution, semantic characteristics, and sometimes temporal dynamics of POIs inside a geographic region can capture its unique land use characteristics.
Junchuan Fan, Gautam Thakur
doaj +1 more source
Fishes, 2021 An estuary region is a complex environment with a transition from fresh to brackish to salt water, and in which some environmental factors change dramatically over small ranges.
Weizhao Meng +6 more
doaj +1 more source