Results 51 to 60 of about 781,263 (268)
Entropy, 2023 Multiscale estimation for geographically weighted regression (GWR) and the related models has attracted much attention due to their superiority. This kind of estimation method will not only improve the accuracy of the coefficient estimators but also ...
Shi-Jie Gao +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Leveraging federalism for flexible and robust management of social‐ecological systems
People and Nature, 2023 Managing social‐ecological systems (SES) requires balancing the need to tailor actions to local heterogeneity and the need to work over large areas to accommodate the extent of SES.
Charles Sims +10 more
doaj +1 more source
Diversity, 2023 Mediterranean wetlands are suitable ecosystems for studying metacommunity theory, since they are isolated ecosystems within a land matrix with well-established limits, often with watersheds destined for agricultural uses.
Juan Diego Gilbert +2 more
doaj +1 more source
Spatial coding for action across spatial scales
Nature Reviews Psychology, 2022 Humans perform goal-directed actions such as reaching for a light switch or grasping a coffee mug thousands of times a day. Behind the scenes of these seemingly simple actions, the brain performs sophisticated calculations to locate the target object of the action and correctly guide the hand towards it.
Fiehler, Katja +2 more
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Factors affecting Bobolink nest survival across grassland types
Avian Conservation and Ecology, 2020 Grassland birds, including Bobolinks (Dolichonyx oryzivorus), have experienced steep population declines across their breeding range in North America. Because of these declines, Bobolinks were listed as threatened by the Ontario and Canadian governments.
Monica A. Fromberger +5 more
doaj
Hydrologic-environmental effects of sponge city under different spatial scales
Journal of Water Reuse and Desalination, 2020 The storm water management models were established at three spatial scales (large, medium, and small) based on a sponge city pilot area in China to explore the hydrological and environmental effects of rainfall conditions and development modes.
Jiake Li +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source