Results 61 to 70 of about 994,786 (316)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The influence of local- and landscape-scale processes on spatial self-organization in estuarine ecosystems

, 2012
Complexity theory proposes that spatial self-organization, the process whereby small-scale, localized interactions among the components of a system generate complex spatial structures at large spatial scales, explains the formation of autogenic spatial ...
Koppel, Johan van de,, Herman, Peter M.J.,, Herman, P.M.J., Bouma, Tjeerd J.,, Van de Koppel, J., Bouma, T.J.   +5 more
core   +1 more source

Correlating Twitter Use with Disaster Resilience at Two Spatial Scales: A Case Study of Hurricane Sandy

Annals of GIS, 2023
Disaster resilience describes the ability of a community to bounce back from disaster impacts by resilience building activities. Social media provides an innovative way to observe human attitudes and responses, especially during disasters.
Kejin Wang, Nina S. N. Lam, Volodymyr Mihunov   +2 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Measuring ecosystem multifunctionality across scales

Environmental Research Letters, 2019
Multifunctionality refers to the capacity of an area to supply multiple ecosystem functions or services. While many conceptual and methodological advances have focused on defining and quantifying multifunctionality, the challenge of dealing with cross ...
Lisanne Hölting, Sander Jacobs, María R Felipe-Lucia, Joachim Maes, Albert V Norström, Tobias Plieninger, Anna F Cord   +6 more
doaj   +1 more source

Percolation Analysis – Archaeological Applications at Widely Different Spatial Scales

Journal of Computer Applications in Archaeology, 2020
This paper provides a summary of the percolation method of cluster analysis, and then describes two detailed archaeological case studies where the technique is applied at significantly different geographical scales.
M. Simon Maddison, Sophie C. Schmidt
doaj   +1 more source

Spatial coding for action across spatial scales

Nature Reviews Psychology, 2022
Humans perform goal-directed actions such as reaching for a light switch or grasping a coffee mug thousands of times a day. Behind the scenes of these seemingly simple actions, the brain performs sophisticated calculations to locate the target object of the action and correctly guide the hand towards it.
Fiehler, Katja, Karimpur, Harun, Justus Liebig University Giessen   +2 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Reproductive performance links to fine-scale spatial patterns of female grey seal relatedness

, 2001
Fine–scale spatial patterns of female relatedness throughout the established grey seal breeding colony of North Rona, Scotland, were investigated by accurate mapping and spatially explicit analyses of a large sample (n=262) of mothers using variation at ...
P. P. Pomeroy, S. D. Twiss, Worthington Wilmer, J., Worthington Wilmer, J, Pomeroy, Patrick, Amos, W, W. Amos, Pomeroy, P.P., J. Worthington Wilmer, Amos, W., Twiss, S.D., Twiss, SD   +11 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source