Results 81 to 90 of about 781,263 (268)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Evaluación del uso de señales visuales y de localización por el colibrí cola-ancha (Selasphorus platycercus) al visitar flores de Penstemon roseus Evaluation of the use of visual and location cues by the Broad-tailed hummingbird (Selasphorus platycercus)foraging in flowers of Penstemon roseus

Revista Mexicana de Biodiversidad, 2012
En los colibríes la memoria espacial desempeña un papel importante durante el forrajeo. Éste se basa en el uso de señales específicas (visuales) o en señales espaciales (localización de flores y plantas con néctar).
Guillermo Pérez, Carlos Lara, Martha Signoret-Poillon, José A. Viccon-Pale   +3 more
doaj  

Using data from camera traps and autonomous recording units to evaluate and improve species-habitat inferences

Avian Conservation and Ecology
In vast and remote regions such as the boreal forest of northern Canada, population dynamics of most wildlife species are poorly understood because of limited sampling.
Laura N. Stewart, Claudia A. Haas, Samuel Haché, Kathy Martin, null Fort Good Hope Renewable Resources Council, null K’áhshó Got’ı̨nę Foundation, null K’áhshó Got’ı̨nę Guardians, null T’sudé Nilįné Tuyeta Management Board, A. Cole Burton   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Habitat amount–fragmentation interactions drive Canada Warbler dynamics across spatial scales

Avian Conservation and Ecology
The Canada Warbler ( Cardellina canadensis ) is a long-distance neotropical migrant that has experienced significant population declines across its range and is listed as threatened in Canada.
Taylor Hart, Erin M Bayne
doaj   +1 more source

On Spatial Resolution in Habitat Models: Can Small-scale Forest Structure Explain Capercaillie Numbers?

Ecology and Society, 2002
This paper explores the effects of spatial resolution on the performance and applicability of habitat models in wildlife management and conservation. A Habitat Suitability Index (HSI) model for the Capercaillie (Tetrao urogallus) in the Bavarian Alps ...
Ilse Storch
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Designing goal-appropriate forest restoration at a broader scale

Environmental Research Letters, 2023
Mingxin Liu, Yuang Chen, Minyu Dou, Xinran Miao, Xiaotong Ren, Shen Zhang, Fangyuan Hua   +6 more
doaj   +1 more source

Global Soil Fauna Metacommunity Patterns: The Roles of Spatial Extent and Environmental Heterogeneity

Diversity
A central debate in metacommunity theory concerns how the relative importance of ecological processes varies with spatial scale. We addressed this by integrating global soil fauna metacommunity datasets to analyze the effects of spatial extent (the ...
Xiaochong Lin, Xiaodong Yang, Pingting Guan, Meixiang Gao, Yunbin Li   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source