Results 71 to 80 of about 781,263 (268)

Interhemispheric comparison of scale‐dependent spatial variation in the structure of intertidal rocky‐shore communities

open access: yesEcosphere, 2020
In rocky intertidal habitats, the pronounced increase in environmental stress with elevation, caused by tides, generates significant vertical variation in community structure.
Alexis M. Catalán   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Environmental heterogeneity at different scales: key factors affecting caddisfly larvae assemblages in standing waters within a lowland river catchment

open access: yesJournal of Limnology, 2016
We examined the importance of environmental parameters at different spatial scales influencing the occurrence of caddisfly larvae at different levels of their organization (species, faunistic metrics and functional groups) in lentic floodplain waters, in
Edyta Buczyńska   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Species Distribution Models in plant conservation science: a comprehensive review with a focus on Iran

open access: yesNatural History Sciences
This review article thoroughly examines the role of Species Distribution Models (SDMs) in plant conservation science, with a specific focus on applications within Iran. Commencing with an extensive methodological approach, involving an exhaustive search
Hooman Babanezhad, Alireza Naqinezhad
doaj   +1 more source

The choice of spatial scales and spatial smoothness priors for various spatial patterns

open access: yesSpatial and Spatio-temporal Epidemiology, 2014
Given the drawbacks for using geo-political areas in mapping outcomes unrelated to geo-politics, a compromise is to aggregate and analyse data at the grid level. This has the advantage of allowing spatial smoothing and modelling at a biologically or physically relevant scale.
Kang, Su   +2 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Impact of Spatial Scales and Spatial Smoothing on the Outcome of Bayesian Spatial Model

open access: yesPLoS ONE, 2013
Discretization of a geographical region is quite common in spatial analysis. There have been few studies into the impact of different geographical scales on the outcome of spatial models for different spatial patterns. This study aims to investigate the impact of spatial scales and spatial smoothing on the outcomes of modelling spatial point-based data.
Kang, Su   +2 more
openaire   +5 more sources

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