Results 51 to 60 of about 47,554 (301)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Development of Spatial Skills in Elementary School Students [PDF]

open access: yesChild Development, 2018
Abstract Through five waves of data collection, this longitudinal study investigated the development of spatial skills in 304 elementary school children (Mage = 7.64 years) as they progressed from the second to fourth grade. The study focused on whether multiple latent classes with different developmental profiles best explain ...
Martha Carr   +5 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Distance, Skill Deepening and Development: Will Peripheral Countries Ever Get Rich? [PDF]

open access: yes
This paper models the relationship between countries' distance from global economic activity, endogenous investments in education, and economic development.
Stephen Redding, Peter K. Schott
core   +4 more sources

Sensitivity to fine-grained and coarse visual information: The effect of blurring on anticipation skill [PDF]

open access: yes, 2009
Copyright @ 2009 Edizione l PozziWe examined skilled tennis players’ ability to perceive fine and coarse information by assessing their ability to predict serve direction under three levels of visual blur.
Bruce Abernethy (389004)   +8 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Influence of proxy data uncertainty on data assimilation for the past climate [PDF]

open access: yesClimate of the Past, 2016
Data assimilation (DA) is an emerging topic in palaeoclimatology and one of the key challenges in this field. Assimilating proxy-based continental mean temperature reconstructions into the MPI-ESM model showed a lack of information propagation to small ...
A. Matsikaris, M. Widmann, J. Jungclaus
doaj   +1 more source

A Player-Centric Approach to Designing Spatial Skill Training Games

open access: yes, 2019
Certain video games show promise as tools for training spa- tial skills, one of the strongest predictors of future success in STEM. However, little is known about the gaming pref- erences of those who would benefit the most from such interventions: low ...
Wauck, Helen C.   +2 more
core   +1 more source

Spatial skills first: The importance of mental rotation for arithmetic skill acquisition

open access: yesJournal of Numerical Cognition, 2019
Considering the importance of arithmetic in school curricula, it is crucial to understand the cognitive processes underlying its successful acquisition. Previous research suggests the involvement of spatial skills, especially during arithmetic skill acquisition.
Carrie Georges   +2 more
openaire   +4 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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